Ambien (zolpidem) and Ambien CR (controlled-release zolpidem) are both medications commonly prescribed to treat insomnia. Although they are similar in purpose, it is crucial to understand their differences and the safety concerns when taken together. This article from SafeHealth 247 provides insights into whether it is safe to take both medications at the same time, along with alternatives and potential risks.
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ToggleWhat Are Ambien and Ambien CR?
Ambien and Ambien CR are both sleep aids that help individuals who struggle with falling asleep. Ambien is an immediate-release medication, meaning it works quickly to help individuals fall asleep. On the other hand, Ambien CR is a controlled-release version that is designed to help people both fall asleep initially and maintain sleep throughout the night. Ambien CR releases the medication in two stages, providing longer-lasting effects.
Both medications belong to the sedative-hypnotic class, which works by acting on the brain to induce a calming effect, promoting relaxation and sleep. While both drugs can be effective for short-term insomnia, the safety of taking them together is a concern.
Is It Safe to Take Ambien and Ambien CR Together?
The short answer is no, it is generally not recommended to take Ambien and Ambien CR together unless your healthcare provider specifically advises it. These medications have sedative effects, and combining them can significantly increase the risk of adverse effects.
Taking both medications simultaneously may lead to excessive sedation. This can manifest as extreme drowsiness, difficulty waking up, or even memory problems. More severe side effects could include impaired motor skills, an increased risk of accidents, and, in rare cases, respiratory depression. This can be particularly dangerous and potentially life-threatening.
Given these potential risks, it’s important to consult with your healthcare provider before combining these medications. In some cases, your doctor may adjust the dosage of one of the medications or suggest alternative treatments that do not carry the same risks.
Possible Risks of Combining Ambien and Ambien CR
When combining Ambien and Ambien CR, the risks largely stem from the enhanced sedative effects of both drugs. Taking both medications at once can cause heightened drowsiness and sedation, which can severely affect your ability to function the following day.
Another risk of combining these medications is cognitive impairment. Excessive sedation may cause confusion, memory lapses, and difficulty thinking clearly. Some individuals might also experience dizziness or lightheadedness, which can increase the chances of falling or getting injured.
In rare cases, when taken in excessive doses, the combined sedative effects of Ambien and Ambien CR could depress breathing, leading to serious complications such as respiratory arrest. This is why combining these medications should only be done under strict medical supervision.

Alternatives to Taking Ambien and Ambien CR Together
If you are struggling with insomnia and considering combining Ambien and Ambien CR, it’s important to explore safer alternatives. One option is to speak with your doctor about adjusting the dosage of your current medications. A healthcare provider may also recommend alternative treatments, including Cognitive Behavioral Therapy for Insomnia (CBT-I), which addresses the underlying causes of sleep issues without the need for medications.
Additionally, at SafeHealth 247, we offer natural sleep aids that can be effective alternatives to prescription medications like Ambien and Ambien CR. These products are designed with your health and safety in mind, helping to promote relaxation and support healthy sleep cycles without the risks associated with pharmaceutical drugs.
Our Weight Loss, Pain Relief, and Sleeping Aid solutions are crafted with natural ingredients known to improve sleep quality and overall wellness. These options may provide the sleep support you need, without the potential side effects of prescription medications.
SafeHealth 247’s Sleep Aid Products
At SafeHealth 247, we understand the importance of a restful night’s sleep and the desire for safe alternatives to prescription medications. If you’re looking for a solution to help you sleep soundly, our Sleeping Aid products might be the perfect choice. Unlike medications like Ambien, our natural sleep aids promote relaxation without the risk of excessive sedation or harmful side effects.
Our Pain Relief and Weight Loss products also support overall wellness, enhancing your health while ensuring a safe, effective approach to sleep. Explore our full range of products designed to promote better sleep and improved well-being, all available at SafeHealth 247.
Final Thoughts
Taking Ambien and Ambien CR together is not recommended due to the increased risks of over-sedation, cognitive impairment, and other potential side effects. If you’re struggling with insomnia, it’s important to consult your healthcare provider to find a safer solution.
At SafeHealth 247, we offer natural, effective alternatives to help you achieve restful sleep. Our products are designed with your safety in mind, so you can enjoy the benefits of a good night’s sleep without compromising your health.